World number one Nadal saw off a battling Nikoloz Basilashvili, the first Georgian in a fourth round in NY, 6-3, 6-3, 6-7 (6/8), 6-4.
"It s a big victory for me", said the 32-year-old Nadal, the champion in 2010, 2013 and 2017.
"A lot of credit to him".
Basilashvili is now ranked 37th, and held his own against the world number one on Sunday.
Having surivived two five-set thrillers to reach the fourth round, Wimbledon runner-up Anderson ran out of steam on Sunday and bowed out tamely.
Nadal trailed by a break in the third set before taking it.
World number one Nadal lost the opening set 6-0 after being outpowered by the Austrian ninth seed in NY. In a duel with the young Croat Coric from Boric del Potro had problems only in the first set, during which the only time in the game lost his serve. Nadal holds a 7 to 3 advantage, though Thiem did beat Nadal earlier this year at the ATP World Tour Masters 1000 in Madrid.
Pliskova, the three-time WTA tour ace leader who briefly ascended to world number one previous year, has surprised Williams before at the US Open, beating her to reach her first Grand Slam final in 2016. The fourth was a wild 81-minute ride that began with Thiem facing break points, saw the Austrian threaten a double break before being pegged back and then a tired Nadal miss a chance to win the match. "It's a dream coming true". "Against Rafa, I've had three very nice experiences and seven awful", said Thiem who turns 25, Monday.
After needing four hours and 23 minutes to beat Khachanov, it means Nadal has spent more than seven-and-a-half hours on court in three days and could face a physical encounter against another heavy hitter in Thiem.
The opener looked to be heading for a tiebreak before Del Potro dispatched a backhand volley to earn himself two more break points in the 10th game.
"I'm very sorry for Dominic", Nadal told a rowdy crowd in Arthur Ashe Stadium.
Aug 31, 2018; New York, NY, USA; Kevin Anderson of South Africa reacts after missing a shot against Denis Shapovalov of Canada (not pictured) in the third round on day five of the US Open at USTA Billie Jean King National Tennis Center. I have a very good relationship with him.
Thiem will next play either world number one Rafael Nadal, who beat Nikoloz Basilashvili in another pre-quarterfinal.
Anderson was hoping to earn a rematch with, who beat him a year ago in the final at Flushing Meadows. "I just hope to keep my level high against John in the next match". "That made things pretty tough".
Coric, 21, is playing in the fourth round at a Slam for the first time.
Isner was a quarter-finalist in 2011 while Ranoic has yet to make the last eight.
Sousa, who totaled 21 winners to 28 unforced errors, has never taken a set off Djokovic in five career head-to-heads. And now he's gone, beaten at the US Open by an opponent ranked outside the top 50 for the first time in his career.
Open put out a statement , explaining the interaction between Lahyani and Kyrgios. "I don't think he's a coach, he's an umpire". The faintest of whispers to a players box - if noticed by the umpire - will earn a warning and in all likeliness, a fine.
Marquez tweeted that the blacklisting began when she made complaints to the show's executive producers, John Wells. Clooney claimed to have done not such thing, writing in a statement, "I was an actor and only an actor".
In Mumbai, the petrol was being sold at Rs 86.56/litre, up by Rs 0.31/litre - the highest ever for any metro city. The price of Brent crude oil went up to $78.05 per barrel on Tuesday from $77.37 per barrel on Monday.
After the loss, Kyrgios was asked what he could learn from the example the 37-year-old had set throughout his career. But, he may need to step out of his comfort zone and play more aggressively if he wants to win this match.
Aretha's phenomenal career spanned five decades and saw her win 18 Grammy awards and sell more than 75 million records. Former president Bill Clinton joked that he and former Secretary of State Hillary Clinton were "Aretha groupies".
Florence's maximum sustained winds were 75 miles per hour as it moved to the west-northwest at 12 miles per hour . As Tropical Storm Gordon heads toward the MS coast, we asked if the storm will affect Fort Worth.
Bournemouth veteran Jermain Defoe says Pierre-Emerick Aubameyang and Alexandre Lacazette must be Arsenal's attacking combination. Danny Ward cancelled out Auba's strike before Lacazette netted an 81st-minute victor following some fine work by Lucas Torreira.
During an appearance on United States television on Monday, D'Amico revealed there is well over $150,000 left of the donations. Appearing on television this week, D'Amico told Kelly: "Every dollar [Bobbitt] ever touched was used for drugs".
A couple of loose points gifted Kanepi a break in the first game of the second set, however, and she couldn't get back on terms. For that bit of good fortune, Serena can thank Kaia Kanepi , who knocked out Halep on the tournament's first day.
Sessions opted out of the probe to avoid a conflict of interest, since he participated in Donald Trump's campaign. Now it's being reported that the president is personally lobbying GOP senators to flip on his attorney general.
Gordon Moving Quickly Across Eastern Gulf Of Mexico
Geo Rodriguez made a decision to go for a walk on Hollywood Beach, north of Miami, on Monday morning and got caught in the storm. The mayor of New Orleans, LaToya Cantrell, promised residents that the city has "the pumps and the power" needed for the storm.
Marcelo 'desperate to join Cristiano Ronaldo at Juventus'
Ronaldo moved to Juventus in the summer following nine years at Real Madrid , and has been getting used to life in northern Italy. It was reported that Juventus' club value ballooned by around £250million due to Ronaldo's arrival at the Old Lady.
Uhuru Leaves to Attend China-Africa Forum in Beijing
According to the World Bank, China has lifted more than 800 million people out of poverty since its economic opening up in 1990. China is investing billions of dollars in aid and projects, making Africa the most focused destination under the BRI.